just some dice I threw around. nothing to see here
Alt text: Five dices. Top left corner is a three, top right corner is a six, bottom left corner is also a six and bottom right corner is two threes forming a straight angle.
At this point it's an internet inside joke, and like any niche inside joke, there's a bit of a rush when you recognize it, that you're in on something special. In the beginning it was mostly just mocking the absurd sudden tone shift in the original Ctrl+Alt+Del comic but like a lot of memes it seems to have evolved and now the fun is creating and finding the loss pattern in unique and different ways.
I am almost certain the only reason it ever blew up was because it's a pretty strong comic, alone, but the fact it can be represented by just a few lines such that nearly any 4 images can become a reference to the comic makes it highly memeable.
It also became memeable and noteworthy because it's it's drastically off tone for the comic strip it came from. Generally a light hearted series and then BAM, have something that in context is utterly brutal.
Nowadays it's so divorced from it's context that it's essentially just a meme.