What are your hidden gem medications/drugs/substances and what makes them ideal for your usecase
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Naltrexone
I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.
It’s a blood pressure medication that acts pretty fast. They give it to people who experience anxiety. If you sometimes get overwhelmed or have anxiety, just pop one of these bad boys and in 30 minutes you’re calmed the fuck down and you can deal with it rationally. 
N.B. Some people have a paradoxical reaction of becoming very depressed temporarily.
Idk if it's on the possible side effects yet but you can find discussions on forums etc going back decades. Very rare, and transient, but if trying for the first time something to be aware of as a risk.
I've read studies claiming it can be used to address traumatic memories as well, because of the chemical calm and how memory works, when you visit one your brain basically opens the file, runs it on your braon, and then re-stores your memory of the current run, where you were chill through the reenactment.
Agreed. For me, if I’m anxious I can’t process as well. Approaching a difficult memory/situation with a relaxed physical state makes the process easier.
There’s less of that “this memory of me being panicked makes me panic” and more of “that memory of me being panicked does not make me panicked now, and I can look at it from a new perspective”
I use nebivolol instead which is highly cardioselective, I recommend it. It has a longer half-life, too. My stress and panic response is a lot more reasonable now.
To what extent does it address the mental aspect or does it do that indirectly on the meta level by making you less anxious because there is less physical anxiety to take notice of?
Edit: I know lots of musicians in orchestras and other professional performers use them to steady hands etc
Part of anxiety is the physical effect of it. The tight chest, the elevated heart beat, the panic mode. It reduces that physical aspect so your brain can focus without FEELING like you’re under attack.