Instant Coffee Is Negatively Associated with Telomere Length: Finding from Observational and Mendelian Randomization Analyses of UK Biobank
Instant Coffee Is Negatively Associated with Telomere Length: Finding from Observational and Mendelian Randomization Analyses of UK Biobank
Telomere length, as a biomarker of accelerated aging, is closely related to many chronic diseases. We aimed to explore the association between coffee consumption and telomere length. Our study included 468,924 participants from the UK Biobank. Multivariate linear models (observational analyses) were...
Hahaha MR-PRESSO in an article about coffee.
Does anyone have ideas as to why instant coffee may have higher levels of lead contamination than regular coffee?
Like does the freeze/spray drying add the potential for it or maybe people who use instant coffee tend to drink more of it or in higher concentrations?
Just some speculation, maybe sourcing cheaper/multiple kinds of beans? Is instant coffee single source? If it's not it could be that some of the beans that are being sourced have higher lead content. I know for example that lead is a problem in tea leaves if not monitored for, as the plants will take up lead from the soil.
Instant gets much higher extraction than any other form of brewing. Hypothetically, it's more likely to extract trace metals at higher concentrations than other methods.
It seems like filtered coffee did not have a negative relationship in this study.
I wonder why? I am not super familiar with the specifics of instant coffee but gather that's it is basically very concentrated.
From my reading, you are correct, but their methodology for determining what type of coffee people drank was very limited and the authors know it. While they didn't see any of the issues they were tracking with normal filtered coffee, they did theorize a reason why instant may be a problem.
From the paper:
The health effects of instant coffee, which varied from other subtypes of coffee, might be caused by their different ingredients. The mineral lead in instant coffee was more abundant than that in other coffee types, and long-term consumption of instant coffee may result in excessive lead [41]. Additional substances added to commercial instant coffee, such as creamer and flavoring agents, might partially explain the negative effect [25,26].
Also:
Instant coffee consumption has been proven to be associated with obesity [44,45]. Compared to women who did not regularly drink coffee, those who drank instant coffee had a higher risk of developing breast cancer [46]. Instant coffee was regarded as a risk factor for Alzheimer’s disease and frailty in the elderly [47,48]. Instant coffee might have the effect of shortening telomere length, and might lead to the occurrence and development of diseases. Therefore, we emphasized the importance of coffee types and the consumption of instant coffee at an appropriate amount. More research needs to identify whether the ingredients in instant coffee results in shorter telomere length.
The paper then goes on to list the limitations they know to exist with their own research and suggest that more work be done.