• A Finnish study indicates that signs of Alzheimer’s disease, specifically elevated brain-related biomarkers, may be detectable in blood from middle age.
• The research, involving 2,051 individuals aged 41 to 90, found these biological changes in adults aged 41 to 56, suggesting they begin decades before symptoms typically appear.
• The Study identified a potential hereditary component, with a parent’s biomarker levels, particularly mothers, possibly linked to similar patterns in their children.
• Factors such as increasing age and kidney disease were associated with higher biomarker levels, and the APOE ε4 gene was linked to higher levels in older individuals.
• Researchers cautioned that while promising, these blood tests are not yet suitable for routine diagnosis and require further standardisation and research across different populations.