2d ago

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com

The work, they said, began decades ago with federal funding for basic research on bacterial immune systems. That led eventually, with more federal support, to the discovery of CRISPR. Federal investment in sequencing the human genome made it possible to identify KJ’s mutation. U.S. funding supported Dr. Liu’s lab and its editing discovery. A federal program to study gene editing supported Dr. Musunuru’s research. Going along in parallel was federally funded work that led to an understanding of KJ’s disease.

Uplifting News @lemmy.world

Null User Object @lemmy.world

2d ago

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com /2025/05/15/health/gene-editing-personalized-rare-disorders.html

New York Times gift articles @sopuli.xyz

silence7 @slrpnk.net

2d ago

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com /2025/05/15/health/gene-editing-personalized-rare-disorders.html

37 comments

Yay now our rich corrupt masters will live even longer!
There's 0% chance this becomes accessible to the regular person under our current global oligarchy

Get ready for wealthy superhumans.
- Gattaca speed run
- What's the over/under for the Eugenics War kick off?
  
  We won't make it far enough for that to happen. Water and temperate climate land wars are up next. Extinction follows.
  
  I give it 6 years tops.
  The bell riots have been pushed back a bit, but it's only a matter of time.
- https://imgur.com/a/p7pyhnW
- Or genetic handicapping. Don't want the poor folk having children that are too healthy or they might actually be better off than their parents.

This isn't news. We were custom editing jeans way back in the 80's. My sister had a bedazzler.
- Yeah, for the last century we've been using starch in laundry to alter jeans and make them feel CRISPR

Finally. CRISPR has been in development for so long I was worried we'd never see it save at least one life.

This along with rna vaccines are one of the few technologies that give me hope for a bit of improvement. If it can become common.
- Correct me if I'm wrong, but I think RNA vaccines predate covid. At least conceptually. I think the covid vaccine was the first to scale it successfully.
  
  Yeah and the big thing is this allows for much more targeted vaccine production. Has massive promise in cancer treatment.
  
  I wrote a term paper on genetic vaccines in 2006. It's been a while.

Lucky kid got fish Linux installed at the factory. Good for him.

Blue!? Can you help me find the DEI hire?
- An Indian guy or a barely functional senior citizen who had brain damage from a parasitic worm.
  Hmmm....
  Can I phone a friend?

That sounds awesome, but why was it necessary to tattoo a blowfish on his cheek??
- They had to tattoo something for the treatment, and the choice was between a blowfish or a penis.
  
  The question stands, why a blowfish?

It took place after Trump was inaugurated, therefore it's his success.
No /s, because you know he's goign to take credit for it
- Honestly, give the bastard credit if he uses this as a reason to stop gutting research and continue supporting it. I mean, won't happen, but I'm definitely sharing this article with every single trumpet I know.
  
  Trump's the kind of guy who will burn down the barn and then take credit for providing a great BBQ.

Magic
- Science
  ...Although at the rate we are going it may well be referred to as such in the stories told about "the before times" as people huddle around the fire.
  
  Magical science?
  Illnesses like KJ’s are the result of a single mutation — an incorrect DNA letter among the three billion in the human genome. Correcting it requires pinpoint targeting in an approach called base editing.
  To accomplish that feat, the treatment is wrapped in fatty lipid molecules to protect it from degradation in the blood on its way to the liver, where the edit will be made. Inside the lipids are instructions that command the cells to produce an enzyme that edits the gene. They also carry a molecular GPS — CRISPR — which was altered to crawl along a person’s DNA until it finds the exact DNA letter that needs to be changed.
- Did you say Magnets?
  
  How do they work?!

Begun, the Eugenics Wars have...
- Wrong series, you have.

37 comments