Universal Coronavirus Vaccine Breakthrough: A Single Shot That Could Protect You From COVID, MERS, and the Common Cold

This would be huge.

Mmm I'm interested to see how the human trials go. It's an interesting idea. Remove the sugars that block a conserved target so you generate antibodies to said conserved target. It's odd to me that this works as well against wild virus that doesn't have the sugars removed. Mechanistically, I'd assume the sugars still block that conserved target in wild virus so the antibodies targeting other less conserved parts are still doing the heavy lifting but then you wouldn't have the cross recognition...idk.