Complete wiring map of an adult fruit fly brain
Researchers fully mapped the connections between neurons for an entire adult fruit fly brain.
That is super cool. Can we might simulate it in a virtual environment? If so, would that be the first matrix like virtual world?
Great, now I'm imagining a group of flies in leather trenchoats.
Mr. Fruiterson, how can you buzz, if you don't have a labium.
I think they already did that with a nematode.
openworm did not map all the neurons yet. But soon 🤞
This will be critical in the development of new fruit fly antidepressants.
This hypes me so much more than GPT-based tools
As neural networks in AI are inspired by nature, new techniques will surely follow the insights gained by such brain mapping research.
Welcome to Microsoft 476! With new features such as fly! That's right! A real simulated fly will help you. Introducing, "the wall" it's where the fly lives! It will stay out of your way unless you call it. Setup your own buzzing noises! It will remind you in perfect stereo fly sounds about your incoming meeting!
can this map be... simulated?
perhaps put into a computer program with simulated inputs from a virtual environment?
I recall seeing the brain of like an amoeba or something very small with only like 100 neurons or something being simulated.
You certainly didn’t see an amoeba brain. They are single cells. I wonder if you heard about the efforts to do the same thing with a nematode?
Openworm
Came here to say the same thing. It worked very well
So to answer what I assume is going to be the most common question here, this is a circuit diagram, but every neuron is like its own little programmable integrated circuit with a small amount of internal memory and those aren't mapped here. So this is an excellent model to explore how neurons connect to each other and get insight into cognition and the function of the brain but it is far from something that can simply be simulated on a computer.
I’m not sure I understand the distinction they’re trying to make between the connectome and the projectome.
The connectome is a map of individual neurones. The projectome is a map of how larger regions interconnect. Particularly the relative strength of the links.
It's the difference between a detailed road map vs the relative road capacity between countries. It cuts out a lot of fine detail to see larger patterns. Both are useful, but in different ways.
I’m actually stunned that a cell-level map, the connectome, is even possible. Are we saying that every fruit fly has all these individual brain cells in this very particular configuration? I always assumed that major brain organelles might be the same from individual to individual but not down to the level of individual neurons. Am I reading something wrong or are individuals really similar as this?
The way I understand it:
Connectome: Displays the synapses between individual neurons
Projectome: The links between regions of the brain via neurons that synapse across regions (basically a subset of the connectome)
So if the connectome is a map of every road, highway, dirt path in the USA, the projectome is a map of the interstates between major cities.
Please someone tell me if this is way off base.
I believe it's this one.
https://flywire.ai/
https://github.com/seung-lab/FlyConnectome
But I also found second one.
https://www.fruitflybrain.org/
https://github.com/fruitflybrain
Old news, but still very cool.
Ok. Now map out how in an entire airport, they ALWAYS seem to manage to find me, after I make lunch. Then as I clap my hands to kill them, they use evasive techniques to avoid being killed. Then they come right back 2 seconds later. Until either I go insane and move, which they follow, or I finally get them with a clap, and they're dead.
I heard that they keep coming back because your efforts to swat at them were clumsy and never a real threat