I've played it for too many hours to count, but gave up at the higher difficulty due to the uncontrollable RNG, you do have to reroll seeds if you want to beat it . Not sure if they reduced the randomness somehow
Once you understand the game mechanics rng becomes much less of a factor. There definitely still is some, it is a roguelike after all, that is part of the fun imo. But it's really not too bad. I find most times that I lose I could have made a better decision somewhere in the run that would have avoided it.