TIL in 1995 NASA tested psychoactive compounds on spiders. Each drug affected their web patterns differently.

Here's a more detailed description for those that like to read up: https://rarehistoricalphotos.com/nasa-spiders-drugs-experiment/

Curiously enough when a similar experiment was first performed decades earlier the original intent was to get the spiders to weave their webs during different times of the day, rather than alter the pattern.