5e has an advantage of not requiring doctorate in quantum physics to run
I would usually be sad to see another original RPG go 5e compatible but Neuroshima was infamously poorly designed ruleset, possibly worse than Shadowrun. I probably won't be running it, but may steal statblocks for my 5e game if I need weird stuff again.
Shadowruns actual rules aren't so bad, character creation is crunchy but you could fit all the non matrix/spirits combat stuff onto maybe 2 sides of a single A4 sheet. The real problem is the editing, that information is spread across the entire rulebook so badly that sometimes it even feels like the information was cut off mid paragraph.
Shadowrun is a "crunchy" game, this means it has a lot of rules, and those rules are not simple. If everyone actually learns the rules for their characters, and people don't do things that are extremely odd, the game can run smoothly.
IIRC from when I ran it, if someone does a normal melee attack (without any magic, hacking, or vehicle shenanigans), it's like 20 steps, and some people can attack 6+ times per round at level 1.
Compare this to a game where at attack is "roll one die, add one number to it. Is it higher than their armour? Then roll a different die and add one number to it. That's the damage you deal".
Edit: Even those of us that love Shadowrun kinda hate Shadowrun. There was also a time when the guy in charge stole a bunch of money from the company, and they didn't have the fund to pay the people who actually worked on their games.
And the book is horrible. Want to throw a grenade? Let me check under grenades... No, not there. Let's check under the throwing skills. Nope, no throwing rules for weapons. Well, maybe under attacks? No, that doesn't have grenade throwing rules either.
Oh look, here in a completely seperate section, contained in an unlisted sidebar, are the rules on grenade throwing.
Oh, you've been shot? It's going to be nearly impossible to cast a spell or fight back. Maybe realistic but the number of characters I spent multiple hours making only to be wounded within moments of play was... greater than two.