Caves of Qud, our favorite science fantasy roguelike where you can clone, befriend, and eat yourself, is leaving early access in December after 15 years of development
A game which I have started numerous times, and then bounced off of due to the archaic control interface. One of these days I'm going to have to knuckle under and learn how to interact with it, as the concept is cool as hell, and I'm sure the controls become intuitive with practice.
Caves of Qud has gotten more approachable than ever, thanks to a complete UI overhaul, gamepad control implementation, and a currently in-beta tutorial that'll arrive in full with the 1.0 launch.
As someone who played roguelikes in the 90's then got frustrated with ancient UI/UX, and therefore also bounced several times, I can confirm that the latest efforts and co-operation with Kitfox have really improved things.
My latest efforts had me playing for several hours almost entirely with the mouse and having fun!
(and then I got stuck in the first basement mission with no way to reach the mission objective; that was less fun)