So apparently if you echo "export PAN_MESA_DEBUG='gofaster'" > ~/.bashrc it will make pretty much everything faster. Now, if you do that but with "gofaster:gofaster" it will make things even FASTER...
...at the expense of breaking some commands here and there. Why is that? How come env values can have this much impact in performance "for free"? This MUST have some caveats, right?
This is just not true. Environment variables are only going to be used by programs that are looking for them specifically. Putting them in your .bashrc as you have done is going to make them only available in contexts where that file is sourced, e.g. interactive command line environments.
...at the expense of breaking some commands here and there...
You probably experience this because you used a single > to overwrite your .bashrc entirely with that single command. Anything that was in that file before is now gone. Using >> will append rather than overwrite.
That variable in particular is probably one used by mesa, a 3D graphics library. It's only going to be used by programs that use the mesa library. I don't know what it does exactly, but there will be documentation somewhere.