This is an important point that should always be asked in this discourse. I mean the critique of casting is certainly valid and in this case the actual meme itself is more about pointing towards the actual racists, but still, being upset for a minority without listening to the actual minority isn't really a good look either.
The reasoning behind the Tilda Swinton one has already been mentioned here, but for example in the Johnny Depp one they apparently even had a Comanche Nation adviser to make sure the representation was done well. That doesn't necessarily make it okay, but why isn't that ever even mentioned in this discourse? I would argue it's still different to do stuff out of ignorance or malice, than just kinda fumble and make bad choices while trying to put in some effort.